TEL. 03-3353-8111
〒162-8666 8-1, Kawada-cho, Shinjuku-ku, Tokyo
As the only department of internal medicine at an endocrine center in Japan, our department treats a wide variety of endocrine disorders (pituitary, thyroid, parathyroid, adrenal, etc.) and is one of the leading facilities in Japan in terms of the number of cases. At the same time, we treat a wide range of diseases closely related to endocrine disorders, such as glucose metabolism abnormalities, lipid disorders, osteoporosis, and obesity. We also specialize in the treatment of hypertension, which affects approximately 40 million Japanese. The Department views essential hypertension as an aggregation of multiple hormonal abnormalities and noninvasively evaluates arterial stiffness, which is closely related to hypertension, to target the blood vessels. By collaborating with other departments within the hospital, we also provide a wide range of services for the diagnosis and treatment of hypertension requiring specialized management, including secondary hypertension such as endocrine hypertension and renal vascular hypertension, and gestational hypertension syndrome.
Through the treatment of these diseases, basic research, and clinical research, our department aims to foster clinicians who can treat the whole body comprehensively and medical researchers who can work at the forefront of international medicine.
In addition to systematic lectures and tutorials focusing on Segment 5 in pre-graduation education, each student is assigned a case for clinical practice and learns the diagnosis of hypertension and endocrine disorders and the process of deciding on a treatment plan under the guidance of a senior physician. In post-graduate education, students can learn the basics of internal medicine as a compulsory training department in the initial clinical training, and at the same time we accept a wide range of applicants for elective training in the second year of training. Based on a five-year curriculum for the latter half of clinical training, students can learn how to determine the indications, their interpretation and treatment methods for specialized tests for endocrine disorders (endocrine stress test, adrenal venous blood sampling, thyroid, parathyroid, and carotid echo techniques, and cytological diagnosis) in terms of medical care. In terms of research, each resident has his or her own research theme and receives guidance on research methods, conference reporting, and composing papers. Those who wish to do so are encouraged to enter clinical graduate school.
In our department, students can obtain qualifications as a specialist in general internal medicine from the Japanese Society of Internal Medicine, a specialist in endocrinology and metabolism (internal medicine) from the Japan Endocrine Society, a specialist in hypertension from the Japanese Society of Hypertension, a specialist certified by the Japanese Thyroid Association, and a specialist in arteriosclerosis from the Japanese Society of Arteriosclerosis.
● Basic/Clinical Research on Growth Hormone Dissecretion Disorders (Acromegaly and Growth Hormone Hyposecretion)
● Basic/Clinical research on prolactin-producing pituitary adenomas
● Basic/Clinical studies on ACTH-producing tumors
● Basic/Clinical Research on Mesencephalopituitaritis
● Basic/Clinical studies on thyroid tumors and Graves' ophthalmopathy
● Basic/Clinical Research on etiology, diagnosis, treatment and prognosis of primary aldosteronism
● Basic/Clinical Research on Etiology, Diagnosis, Treatment and Prognosis of Adrenogenic Cushing's Syndrome
● Basic/Clinical Studies on Etiology, Diagnosis, Treatment, and Prognosis of (Malignant) Pheochromocytoma
● Basic/Clinical Research on etiology and treatment of refractory hypertension
● Basic/Clinical Research on soluble (pro)renin receptor
Professor and Division head Atsuhiro Ichihara
Lecturer Daisuke WATANABE
Lecturer Yasufumi SEKI
● Mechanisms of visceral fat gain in hypogonadism of growth hormone secretion
● Analysis of blood pressure regulation by the RAS and sympathetic nervous system in the mesencephalic pituitary gland
● Functional analysis of vasopressin and (pro)renin receptors coexisting in the posterior pituitary gland
● Mechanisms of tissue RAS-dependent organ damage in thyroid dysfunction
● Ectopic receptor expression analysis in adrenal tumors to analyze the mechanism of function acquisition and tumorigenesis
● Identification of genes involved in the invasiveness of endocrine tumor cells
● Establishment of endocrine gland tissue reconstruction using iPS cells
● Investigation of the role and regulatory mechanism of (pro)renin receptors in physiology and various pathological conditions
● Investigation of the regulatory mechanism of neuro-hydrodynamic factors and the inhibitory effect on atherosclerosis by drugs for lifestyle-related diseases (hypertension, diabetes, and dyslipidemia).
● Endocrine stress testing and evaluation
● Evaluation of vascular flexibility and sympathetic nerve function
● Practice of Thyroid echocardiography and carotid artery echocardiography
● Pituitary and adrenal imaging and adrenal vein sampling
Research Achievements Database
〒162-8666
8-1, Kawada-cho, Shinjuku-ku, Tokyo
TEL +81-3-3353-8111