TEL. 03-3353-8111
〒162-8666 8-1, Kawada-cho, Shinjuku-ku, Tokyo
Our department consists of two full-time physicians, one part-time physician, and one concurrent faculty member. As part of the "Transfusion and Cell Processing Unit," a clinical support division, we are engaged in a wide range of essential medical services.
In terms of transfusion services, we manage and supply all blood products used within the hospital, including red blood cells, platelets, and fresh frozen plasma. We also oversee the centralized management and distribution of plasma-derived products such as human coagulation factors, immunoglobulins, and albumin.
In the area of cell processing, we are responsible for the preparation and supply of regenerative medicine products, cell-based therapies for clinical research and treatment, and the collection of source cells for CAR (Chimeric Antigen Receptor) T-cell therapy.
We actively engage in research and education. The department operates three research laboratories and a GCTP-compliant Cell Processing Center (CPC), which meets the standards for the manufacturing and quality control of regenerative medical products. In cancer immunotherapy research, we utilize cell culture systems and flow cytometry to develop novel therapeutic strategies and identify potential biomarkers. We also collaborate with other clinical departments in conducting clinical trials under the Act on the Safety of Regenerative Medicine and investigational studies of regenerative products.
Additionally, we are conducting research to uncover the pathogenesis of congenital disorders using cytogenetic analyses and disease model cells created via genome editing technologies. For diseases such as congenital hemolytic anemia, pure red cell aplasia, and bone marrow failure syndromes, we collect specimens from medical institutions nationwide to perform genetic diagnoses and identify novel disease-related genes.
In education, we offer a comprehensive curriculum ranging from the fundamentals of transfusion medicine and laboratory testing to advanced elective training in cell culture and cell therapy. Through research closely linked to clinical practice, we support medical students in developing the knowledge and skills necessary for the future of medicine.
(Undergraduate education and training)
Segment 7
Segment 8
Segment 9
(Post-graduate education)
Orientation for trainees in medical training
Orientation for post-graduate clinical training center
Blood transfusion workshop for nurses
(Training for extramural personnel)
Japanese Society of Blood Transfusion and Cell Therapy Certified Technician System, Designated Institution Training
Training at facilities designated by the Japanese Society of Blood Transfusion and Cell Therapy (JSBTCT) for the Blood Transfusion Nurse System
Training at facilities affiliated with the Japanese Society of Blood Transfusion and Cell Therapy's Cell Culture Manager Certification System (tentative)
• Development and clinical trials of combination cancer immunotherapies
• Elucidation of immune exhaustion mechanisms in patients with advanced cancer and development of novel immunotherapies to overcome exhaustion
• Pathophysiological analysis aimed at developing treatments for leukoencephalopathy
• Identification of novel biomarkers for Diamond–Blackfan anemia
• Development of gene therapy using pyruvate kinase deficiency model mice
• Development of innovative therapies for congenital hemolytic anemia and bone marrow failure syndromes using iPS cells
• Identification of novel causative genes of congenital hemolytic anemia
• Identification of genomic biomarkers for predicting anticancer drug sensitivity and adverse reaction risks, contributing to personalized cancer therapy
• Establishment of a genomic medicine framework through pharmacogenomics and cancer genome analysis
Professor Hirohito KOBAYASHI
Visiting Professor Shigetaka SHIMODAIRA
Lecturer Keiko Shimojima YAMAMOTO
Project Professor(Concurrent Appointment) Hitoshi KANNO
Research Achievements Database
〒162-8666
8-1, Kawada-cho, Shinjuku-ku, Tokyo
TEL +81-3-3353-8111