研修希望の方へ 最近の論文
最近の論文

当センターは世界最大級のリウマチセンターであり、最先端の研究活動とその結果得られる最新情報の発信は我々に与えられた重要な使命の一つと考えております。これまでにIORRAコホートや病棟で蓄積された数多くの症例を背景とした臨床研究、多彩なフィールドでの基礎研究などで多くの業績をあげており、また世界最大級の患者数を誇る施設であるため、貴重な症例の報告も積極的におこなっています。

関節リウマチ

1. Yamaguchi R, Tanaka E, Nakajima A, Inoue E, Abe M, Sugano E, Sugitani N, Saka K, Ochiai M, Higuchi Y, Sugimoto N, Ikari K, Yamanaka H, Harigai M. Risk of herpes zoster in patients with rheumatoid arthritis in the biologics era from 2011 to 2015 and its association with methotrexate, biologics, and corticosteroids Mod Rheumatol. 2021 Sep 13:roab026. doi: 10.1093/mr/roab026. Online ahead of print.doi: 10.1093/mr/roab026 PMID34897494
2011~2015年の間に通院した関節リウマチ患者を対象に、帯状疱疹について調査した。2005~2010年の前回調査と比較し、帯状疱疹の罹患しやすさに大きな変化はなかった。帯状疱疹罹患に影響する因子は、前回調査は高齢、ステロイド服用量、メトトレキサート服用であったが、今回は高齢、メトトレキサート服用、生物学的製剤使用であり、ステロイドの影響ははっきりしなかった。

2. Okamoto Y, Devoe S, Seto N, Minarchick V, Wilson T, Rothfuss HM, Mohning MP, Arbet J, Kroehl M, Visser A, August J, Thomas SM, Charry LL, Fleischer C, Feser ML, Frazer-Abel AA, Norris JM, Cherrington BD, Janssen WJ, Kaplan MJ, Deane KD, Holers VM, Demoruelle MK. Association of Sputum Neutrophil Extracellular Trap Subsets With IgA Anti-Citrullinated Protein Antibodies in Subjects at Risk for Rheumatoid Arthritis Arthritis Rheumatol. 2021 Aug 9. doi: 10.1002/art.41948. Online ahead of print.doi: 10.1002/art.41948 PMID34369110
好中球細胞外トラップス(NETs)形成の過程で産生されるシトルリン化ヒストンH3(cit-H3)は、抗CCP抗体が認識する対応抗原の1つです。将来的な関節リウマチ発症ハイリスク者の気道粘膜では、cit-H3産生を伴うNETs形成が亢進しており、気道でのIgA型抗CCP抗体産生と関連することを報告しました。

3. Nakajima A, Sakai R, Inoue E, Harigai M. Geographic variations in rheumatoid arthritis treatment in Japan: A nationwide retrospective study using the national database of health insurance claims and specific health checkups of Japan Mod Rheumatol. 2021 Apr 15:1-9. doi: 10.1080/14397595.2021.1910615. Online ahead of print.doi: 10.1080/14397595.2021.1910615 PMID33818268                               2017年度のNational Databaseを用いて、わが国の82.5万人の関節リウマチ(RA)患者における専門施設受診状況とRA治療薬の使用状況を都道府県別に示した。RA患者の31.8%はRA専門施設を受診しておらず、約4分の1の都道府県では、専門施設未受診割合が全国平均よりも10%以上高かった。RA薬物治療の使用実態は都道府県および専門・非専門施設の間で異なっていた。

4. Kojima M, Hasegawa M, Hirata S, Ito H, Kaneko Y, Kishimoto M, Kohno M, Kojima T, Matsushita I, Mori M, Morinobu A, Murashima A, Nishida K, Seto Y, Sobue Y, Sugihara T, Tanaka E, Nakayama T, Kawahito Y, Harigai M. Patients' perspectives of rheumatoid arthritis treatment: a questionnaire survey for the 2020 update of the Japan college of rheumatology clinical practice guidelines Mod Rheumatol. 2021 May 19:1-6. doi: 10.1080/14397595.2021.1913276. Online ahead of print.doi: 10.1080/14397595.2021.1913276 PMID33853492

5. Sugihara T, Kawahito Y, Morinobu A, Kaneko Y, Seto Y, Kojima T, Ito H, Kohno M, Nakayama T, Sobue Y, Nishida K, Matsushita I, Murashima A, Mori M, Tanaka E, Hirata S, Kishimoto M, Yamanaka H, Kojima M, Harigai M. Systematic review for the treatment of older rheumatoid arthritis patients informing the 2020 update of the Japan College of Rheumatology clinical practice guidelines for the management of rheumatoid arthritis Mod Rheumatol. 2021 May 19:1912922. doi: 10.1080/14397595.2021.1912922. Online ahead of print.doi: 10.1080/14397595.2021.1912922 PMID34931249

6. Sobue Y, Kojima M, Kojima T, Ito H, Nishida K, Matsushita I, Hirata S, Kaneko Y, Kishimoto M, Kohno M, Murashima A, Morinobu A, Mori M, Nakayama T, Sugihara T, Seto Y, Tanaka E, Hasegawa M, Kawahito Y, Harigai M. Patient satisfaction with total joint replacement surgery for rheumatoid arthritis: a questionnaire survey for the 2020 update of the Japan college of rheumatology clinical practice guidelines Mod Rheumatol. 2021 Mar 16:1892258. doi: 10.1080/14397595.2021.1892258. Online ahead of print.doi: 10.1080/14397595.2021.1892258 PMID34922365

7. Sugihara T, Kawahito Y, Morinobu A, Kaneko Y, Seto Y, Kojima T, Ito H, Kohno M, Nakayama T, Sobue Y, Nishida K, Matsushita I, Murashima A, Mori M, Tanaka E, Hirata S, Kishimoto M, Yamanaka H, Kojima M, Harigai M. Systematic review for the treatment of older rheumatoid arthritis patients informing the 2020 update of the Japan College of Rheumatology clinical practice guidelines for the management of rheumatoid arthritis Mod Rheumatol. 2021 May 19:1-15. doi: 10.1080/14397595.2021.1912922. Online ahead of print.doi: 10.1080/14397595.2021.1912922 PMID33853484

8. Kojima M, Hasegawa M, Hirata S, Ito H, Kaneko Y, Kishimoto M, Kohno M, Kojima T, Matsushita I, Mori M, Morinobu A, Murashima A, Nishida K, Seto Y, Sobue Y, Sugihara T, Tanaka E, Nakayama T, Kawahito Y, Harigai M. Patients' perspectives of rheumatoid arthritis treatment: a questionnaire survey for the 2020 update of the Japan college of rheumatology clinical practice guidelines Mod Rheumatol. 2021 May 19:1913276. doi: 10.1080/14397595.2021.1913276. Online ahead of print.doi: 10.1080/14397595.2021.1913276PMID34931254

9. Ito H, Murata K, Sobue Y, Kojima T, Nishida K, Matsushita I, Kawahito Y, Kojima M, Hirata S, Kaneko Y, Kishimoto M, Kohno M, Mori M, Morinobu A, Murashima A, Seto Y, Sugihara T, Tanaka E, Nakayama T, Harigai M. Comprehensive risk analysis of postoperative complications in patients with rheumatoid arthritis for the 2020 update of the Japan College of Rheumatology clinical practice guidelines for the management of rheumatoid arthritis Mod Rheumatol. 2021 Aug 31:1-11. doi: 10.1080/14397595.2021.1913824. Online ahead of print.doi: 10.1080/14397595.2021.1913824 PMID33855932

10. Kuramoto N, Saito S, Fujii T, Kaneko Y, Saito R, Tanaka M, Takada H, Nakano K, Saito K, Sugimoto N, Sasaki S, Harigai M, Suzuki Y. Characteristics of rheumatoid arthritis with immunodeficiency-associated lymphoproliferative disorders to regress spontaneously by the withdrawal of methotrexate and their clinical course: A retrospective, multicenter, case-control study Mod Rheumatol. 2021 Mar 8:1879362. doi: 10.1080/14397595.2021.1879362. Online ahead of print.doi: 10.1080/14397595.2021.1879362PMID34919729

11. Saito R, Tanaka M, Ito H, Kuramoto N, Fujii T, Saito S, Kaneko Y, Nakano K, Saito K, Takada H, Sugimoto N, Sasaki S, Harigai M, Suzuki Y. Overall survival and post-spontaneous regression relapse-free survival of patients with lymphoproliferative disorders associated with rheumatoid arthritis: a multi-center retrospective cohort study Mod Rheumatol. 2021 Feb 15:1866837. doi: 10.1080/14397595.2020.1866837. Online ahead of print.doi: 10.1080/14397595.2020.1866837 PMID34919718

12. Furuya T, Oh K, Ikari K, Inoue E, Tanaka E, Yamanaka H, Harigai M. Factors associated with frailty in Japanese patients with rheumatoid arthritis: results from the Institute of Rheumatology Rheumatoid Arthritis cohort study Clin Rheumatol. 2021 Sep 29. doi: 10.1007/s10067-021-05938-7. Online ahead of print.doi: 10.1007/s10067-021-05938-7PMID34586516

13. Oh K, Furuya T, Inoue E, Tanaka E, Ikari K, Taniguchi A, Yamanaka H, Okazaki K, Harigai M. A simple screening test to assess risk of falls in Japanese patients with rheumatoid arthritis: Results from the IORRA cohort study Mod Rheumatol. 2021 Mar;31(2):506-509. doi: 10.1080/14397595.2020.1746016. Epub 2020 Apr 14.doi: 10.1080/14397595.2020.1746016 PMID32202187

14. Saito R, Tanaka M, Ito H, Kuramoto N, Fujii T, Saito S, Kaneko Y, Nakano K, Saito K, Takada H, Sugimoto N, Sasaki S, Harigai M, Suzuki Y. Overall survival and post-spontaneous regression relapse-free survival of patients with lymphoproliferative disorders associated with rheumatoid arthritis: a multi-center retrospective cohort study Mod Rheumatol. 2021 Feb 15:1-16. doi: 10.1080/14397595.2020.1866837. Online ahead of print.doi: 10.1080/14397595.2020.1866837 PMID33336615

15. Abe Y, Saeki K, Dobashi H, Kawakami T, Hayashi T, Kobayashi M, Kaname S, Harigai M, Tamura N. Clinical characteristics and social productivity levels of patients with malignant rheumatoid arthritis based on a nationwide clinical database in Japan: annual survey from 2003 to 2013 Mod Rheumatol. 2021 May;31(3):621-628. doi: 10.1080/14397595.2020.1795390. Epub 2020 Jul 31.doi: 10.1080/14397595.2020.1795390 PMID32657636

16. Kuramoto N, Saito S, Fujii T, Kaneko Y, Saito R, Tanaka M, Takada H, Nakano K, Saito K, Sugimoto N, Sasaki S, Harigai M, Suzuki Y. Characteristics of rheumatoid arthritis with immunodeficiency-associated lymphoproliferative disorders to regress spontaneously by the withdrawal of methotrexate and their clinical course: A retrospective, multicenter, case-control study Mod Rheumatol. 2021 Mar 8:1-16. doi: 10.1080/14397595.2021.1879362. Online ahead of print.doi: 10.1080/14397595.2021.1879362 PMID33496194

17. Yamaoka K, Tanaka Y, Kameda H, Khan N, Sasaki N, Harigai M, Song Y, Zhang Y, Takeuchi T. The Safety Profile of Upadacitinib in Patients with Rheumatoid Arthritis in Japan Drug Saf. 2021 Jun;44(6):711-722. doi: 10.1007/s40264-021-01067-x. Epub 2021 May 27.doi: 10.1007/s40264-021-01067-x PMID34041702

18. Nakayama M, Furuya T, Inoue E, Tanaka E, Ikari K, Taniguchi A, Yamanaka H, Harigai M. Adherence to denosumab for the treatment of osteoporosis in Japanese patients with rheumatoid arthritis: Results from the IORRA cohort study Mod Rheumatol. 2021 Mar;31(2):510-513. doi: 10.1080/14397595.2020.1789319. Epub 2020 Jul 15.doi: 10.1080/14397595.2020.1789319 PMID32609062

19. Nakayama M, Furuya T, Inoue E, Tanaka E, Ikari K, Yamanaka H, Harigai M. Vitamin D deficiency is a risk factor for new fractures in Japanese postmenopausal women with rheumatoid arthritis: results from the IORRA cohort study Arch Osteoporos. 2021 Aug 3;16(1):119. doi: 10.1007/s11657-021-00982-x.doi: 10.1007/s11657-021-00982-x PMID34342724

20. Tanaka Y, Kameda H, Saito K, Kaneko Y, Tanaka E, Yasuda S, Tamura N, Fujio K, Fujii T, Kojima T, Anzai T, Hamada C, Fujino Y, Matsuda S, Kohsaka H. Response to tocilizumab and work productivity in patients with rheumatoid arthritis: 2-year follow-up of FIRST ACT-SC study Mod Rheumatol. 2021 Jan;31(1):42-52. doi: 10.1080/14397595.2019.1709681. Epub 2020 Jan 20.doi: 10.1080/14397595.2019.1709681 PMID31903822

21. Ochiai M, Tanaka E, Sato E, Inoue E, Abe M, Saka K, Sugano E, Sugitani N, Higuchi Y, Yamaguchi R, Sugimoto N, Ikari K, Nakajima A, Yamanaka H, Harigai M. Successful discontinuation of biological disease-modifying antirheumatic drugs in patients with rheumatoid arthritis in real-world settings Mod Rheumatol. 2021 Jul;31(4):790-795. doi: 10.1080/14397595.2021.1883252. Epub 2021 Mar 1.doi: 10.1080/14397595.2021.1883252 PMID33538611

22. Sugihara T, Ishizaki T, Onoguchi W, Baba H, Matsumoto T, Iga S, Kubo K, Kamiya M, Hirano F, Hosoya T, Miyasaka N, Harigai M. Effectiveness and safety of treat-to-target strategy in elderly-onset rheumatoid arthritis: a 3-year prospective observational study Rheumatology (Oxford). 2021 Sep 1;60(9):4252-4261. doi: 10.1093/rheumatology/keaa922.doi: 10.1093/rheumatology/keaa922PMID33410490

23. Hirose W, Harigai M, Amano K, Hidaka T, Itoh K, Aoki K, Nakashima M, Nagasawa H, Komano Y, Nanki T; TOF-ABT Study Group. Impact of the HLA-DRB1 shared epitope on responses to treatment with tofacitinib or abatacept in patients with rheumatoid arthritis Arthritis Res Ther. 2021 Aug 31;23(1):228. doi: 10.1186/s13075-021-02612-w.doi: 10.1186/s13075-021-02612-w PMID34465391

24. Oh K, Furuya T, Ikari K, Inoue E, Tanaka E, Yamanaka H, Okazaki K, Harigai M. Polypharmacy, declined walking speed, bent back, and disability associated with a history of falls in Japanese patients with rheumatoid arthritis: Results from the IORRA cohort study Mod Rheumatol. 2021 May;31(3):764-767. doi: 10.1080/14397595.2020.1812200. Epub 2020 Sep 7.doi: 10.1080/14397595.2020.1812200 PMID32812455

25. Takada H, Kaneko Y, Nakano K, Tanaka M, Fujii T, Saito K, Sugimoto N, Sasaki S, Saito S, Saito R, Kuramoto N, Harigai M, Suzuki Y. Clinicopathological characteristics of lymphoproliferative disorders in 232 patients with rheumatoid arthritis in Japan: A retrospective, multicenter, descriptive study Mod Rheumatol. 2021 Apr 6:1899570. doi: 10.1080/14397595.2021.1899570. Online ahead of print.doi: 10.1080/14397595.2021.1899570 PMID34919724

26. Honda S, Sakai R, Inoue E, Majima M, Konda N, Takada H, Kihara M, Yajima N, Nanki T, Yamamoto K, Takeuchi T, Harigai M. Association of methotrexate use and lymphoproliferative disorder in patients with rheumatoid arthritis: Results from a Japanese multi-institutional retrospective study Mod Rheumatol. 2021 Mar 1:1869370. doi: 10.1080/14397595.2020.1869370. Online ahead of print.doi: 10.1080/14397595.2020.1869370 PMID34919716

27. Tanaka E, Kawahito Y, Kohno M, Hirata S, Kishimoto M, Kaneko Y, Tamai H, Seto Y, Morinobu A, Sugihara T, Murashima A, Kojima M, Mori M, Ito H, Kojima T, Sobue Y, Nishida K, Matsushita I, Nakayama T, Yamanaka H, Harigai M. Systematic review and meta-analysis of biosimilar for the treatment of rheumatoid arthritis informing the 2020 update of the Japan College of Rheumatology clinical practice guidelines for the management of rheumatoid arthritis Mod Rheumatol. 2021 Apr 6:1899591. doi: 10.1080/14397595.2021.1899591. Online ahead of print.doi: 10.1080/14397595.2021.1899591 PMID34922387

28. Sobue Y, Kojima T, Ito H, Nishida K, Matsushita I, Kaneko Y, Kishimoto M, Kohno M, Sugihara T, Seto Y, Tanaka E, Nakayama T, Hirata S, Murashima A, Morinobu A, Mori M, Kojima M, Kawahito Y, Harigai M. Does exercise therapy improve patient-reported outcomes in rheumatoid arthritis? A systematic review and meta-analysis for the update of the 2020 JCR guidelines for the management of rheumatoid arthritis Mod Rheumatol. 2021 Feb 22:1886653. doi: 10.1080/14397595.2021.1886653. Online ahead of print.doi: 10.1080/14397595.2021.1886653 PMID34927208

29. Ito H, Murata K, Sobue Y, Kojima T, Nishida K, Matsushita I, Kawahito Y, Kojima M, Hirata S, Kaneko Y, Kishimoto M, Kohno M, Mori M, Morinobu A, Murashima A, Seto Y, Sugihara T, Tanaka E, Nakayama T, Harigai M. Comprehensive risk analysis of postoperative complications in patients with rheumatoid arthritis for the 2020 update of the Japan College of Rheumatology clinical practice guidelines for the management of rheumatoid arthritis Mod Rheumatol. 2021 Aug 31:1913824. doi: 10.1080/14397595.2021.1913824. Online ahead of print.doi: 10.1080/14397595.2021.1913824 PMID34928379

30. Tanaka E, Kawahito Y, Kohno M, Hirata S, Kishimoto M, Kaneko Y, Tamai H, Seto Y, Morinobu A, Sugihara T, Murashima A, Kojima M, Mori M, Ito H, Kojima T, Sobue Y, Nishida K, Matsushita I, Nakayama T, Yamanaka H, Harigai M. Systematic review and meta-analysis of biosimilar for the treatment of rheumatoid arthritis informing the 2020 update of the Japan College of Rheumatology clinical practice guidelines for the management of rheumatoid arthritis Mod Rheumatol. 2021 Apr 6:1-13. doi: 10.1080/14397595.2021.1899591. Online ahead of print.doi: 10.1080/14397595.2021.1899591 PMID33706664

31. Sobue Y, Kojima T, Ito H, Nishida K, Matsushita I, Kaneko Y, Kishimoto M, Kohno M, Sugihara T, Seto Y, Tanaka E, Nakayama T, Hirata S, Murashima A, Morinobu A, Mori M, Kojima M, Kawahito Y, Harigai M. Does exercise therapy improve patient-reported outcomes in rheumatoid arthritis? A systematic review and meta-analysis for the update of the 2020 JCR guidelines for the management of rheumatoid arthritis Mod Rheumatol. 2021 Feb 22:1-14. doi: 10.1080/14397595.2021.1886653. Online ahead of print.doi: 10.1080/14397595.2021.1886653 PMID33565350

32. Sobue Y, Kojima M, Kojima T, Ito H, Nishida K, Matsushita I, Hirata S, Kaneko Y, Kishimoto M, Kohno M, Murashima A, Morinobu A, Mori M, Nakayama T, Sugihara T, Seto Y, Tanaka E, Hasegawa M, Kawahito Y, Harigai M. Patient satisfaction with total joint replacement surgery for rheumatoid arthritis: a questionnaire survey for the 2020 update of the Japan college of rheumatology clinical practice guidelines Mod Rheumatol. 2021 Mar 16:1-6. doi: 10.1080/14397595.2021.1892258. Online ahead of print.doi: 10.1080/14397595.2021.1892258 PMID33617382

33. Takada H, Kaneko Y, Nakano K, Tanaka M, Fujii T, Saito K, Sugimoto N, Sasaki S, Saito S, Saito R, Kuramoto N, Harigai M, Suzuki Y. Clinicopathological characteristics of lymphoproliferative disorders in 232 patients with rheumatoid arthritis in Japan: A retrospective, multicenter, descriptive study Mod Rheumatol. 2021 Apr 6:1-9. doi: 10.1080/14397595.2021.1899570. Online ahead of print.doi: 10.1080/14397595.2021.1899570 PMID33705243

34. Harigai M, Tsuritani K, Yoshizawa Y, Atsumi T, Tanaka Y. Long-term safety and effectiveness of abatacept in Japanese patients with rheumatoid arthritis: 3-year follow-up of a postmarketing surveillance Mod Rheumatol. 2021 Sep 4:roab050. doi: 10.1093/mr/roab050. Online ahead of print.doi: 10.1093/mr/roab050 PMID34910191

35. Nakajima A, Sakai R, Inoue E, Harigai M. Geographic variations in rheumatoid arthritis treatment in Japan: A nationwide retrospective study using the national database of health insurance claims and specific health checkups of Japan Mod Rheumatol. 2021 Apr 15:1910615. doi: 10.1080/14397595.2021.1910615. Online ahead of print.doi: 10.1080/14397595.2021.1910615 PMID34922382

36. Sugano E, Tanaka E, Inoue E, Sakai R, Abe M, Saka K, Sugitani N, Ochiai M, Yamaguchi R, Higuchi Y, Sugimoto N, Ikari K, Nakajima A, Yamanaka H, Harigai M. Differences in patients' population and efficacy/effectiveness of biologic disease-modifying antirheumatic drugs between randomized controlled trials and real-world settings in patients with rheumatoid arthritis - using the IORRA cohort Mod Rheumatol. 2021 Sep 10:roab067. doi: 10.1093/mr/roab067. Online ahead of print.doi: 10.1093/mr/roab067 PMID34918127

37. Higuchi T, Tanaka E, Inoue E, Abe M, Saka K, Sugano E, Sugitani N, Higuchi Y, Ochiai M, Yamaguchi R, Sugimoto N, Ikari K, Yamanaka H, Harigai M. Impact of Concomitant Chronic Kidney Disease on Hospitalized Infections and Remission in Patients with Rheumatoid Arthritis: Results from the IORRA Cohort Mod Rheumatol. 2021 Nov 9:roab082. doi: 10.1093/mr/roab082. Online ahead of print.doi: 10.1093/mr/roab082 PMID34751783

38. Honda S, Sakai R, Inoue E, Majima M, Konda N, Takada H, Kihara M, Yajima N, Nanki T, Yamamoto K, Takeuchi T, Harigai M. Association of methotrexate use and lymphoproliferative disorder in patients with rheumatoid arthritis: Results from a Japanese multi-institutional retrospective study Mod Rheumatol. 2021 Mar 1:1-14. doi: 10.1080/14397595.2020.1869370. Online ahead of print.doi: 10.1080/14397595.2020.1869370 PMID33428479

37. Higuchi T, Tanaka E, Inoue E, Abe M, Saka K, Sugano E, Sugitani N, Higuchi Y, Ochiai M, Yamaguchi R, Sugimoto N, Ikari K, Yamanaka H, Harigai M. Impact of Concomitant Chronic Kidney Disease on Hospitalized Infections and Remission in Patients with Rheumatoid Arthritis: Results from the IORRA Cohort Mod Rheumatol. 2021 Nov 9:roab082. doi: 10.1093/mr/roab082. Online ahead of print.doi: 10.1093/mr/roab082 PMID34751783

38. Honda S, Sakai R, Inoue E, Majima M, Konda N, Takada H, Kihara M, Yajima N, Nanki T, Yamamoto K, Takeuchi T, Harigai M. Association of methotrexate use and lymphoproliferative disorder in patients with rheumatoid arthritis: Results from a Japanese multi-institutional retrospective study Mod Rheumatol. 2021 Mar 1:1-14. doi: 10.1080/14397595.2020.1869370. Online ahead of print.doi: 10.1080/14397595.2020.1869370 PMID33428479

39. Tamura N, Azuma T, Misaki K, Yamaguchi R, Hirano F, Sugiyama E, Kanai D, Murakawa Y, Oribe M, Kimata T, Aoki K, Sugiura T, Takasugi K, Takakubo Y, Tomita Y, Isozaki T, Nanki T, Katsuyama N, Kuroiwa T, Oshikawa H, Kaneko M, Fujinaga H, Saito K, Tanaka E, Inoue E, Yoshizawa Y, Matsumoto S, Yamanaka H, Harigai M. Effectiveness and safety of subcutaneous abatacept in biologic-naïve RA patients at Week 52: A Japanese multicentre investigational study (ORIGAMI study) Mod Rheumatol. 2021 Oct 8:roab090. doi: 10.1093/mr/roab090. Online ahead of print.doi: 10.1093/mr/roab090 PMID34915575

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 リウマチ整形

1. Yano K, Ikari K, Tobimatsu H, Okazaki K. Patient-Reported and Radiographic Outcomes of Joint-Preserving Surgery for Rheumatoid Forefoot Deformities: A Retrospective Case Series with Mean Follow-up of 6 Years J Bone Joint Surg Am. 2021 Mar 17;103(6):506-516. doi: 10.2106/JBJS.20.01144.doi: 10.2106/JBJS.20.01144 PMID33475311
我々はリウマチ性の外反母趾に対する手術方法として第1中足骨近位回旋閉鎖式骨切り術という術式を開発し、2013年にModern Rheumatologyで良好な短期成績を報告していますが、今回矢野先生が最低観察期間5年の長期成績をまとめ、整形外科分野のトップジャーナルであるJ Bone Joint Surg Am.に報告することが出来ました。 第1中足骨近位回旋閉鎖式骨切り術を中心としたリウマチ前足部手術により、PROMがMCIDを超えて有意に改善し、画像的にも有意な改善を示し、再手術をエンドポイントとした生存曲線解析で6年で90%が再手術を回避出来ていることを示しています。

2. Mochizuki T, Yano K, Ikari K, Okazaki K. Sarcopenia in Japanese younger patients with rheumatoid arthritis: A cross-sectional study Mod Rheumatol. 2021 Mar;31(2):504-505. doi: 10.1080/14397595.2020.1740411. Epub 2020 Mar 30.doi: 10.1080/14397595.2020.1740411 PMID32148139

3. Mochizuki T, Yano K, Ikari K, Hiroshima R, Nasu Y, Okazaki K. Three-year results of denosumab treatment for osteoporosis in women with rheumatoid arthritis and primary osteoporosis: A clinical observational study Mod Rheumatol. 2021 May;31(3):600-606. doi: 10.1080/14397595.2020.1812793. Epub 2020 Sep 10.doi: 10.1080/14397595.2020.1812793 PMID32815449

4. Mochizuki T, Yano K, Ikari K, Okazaki K. Effects of the COVID-19 pandemic on body composition among patients with rheumatoid arthritis Mod Rheumatol. 2021 Sep 15:roab018. doi: 10.1093/mr/roab018. Online ahead of print.doi: 10.1093/mr/roab018 PMID34894260

5. Mochizuki T, Yano K, Ikari K, Hiroshima R, Fukagawa S, Nasu Y, Okazaki K. Association between low back pain and quality of life in patients with rheumatoid arthritis according to patient-reported outcomes using the Japanese Orthopaedic Association Back Pain Evaluation Questionnaire (JOABPEQ): A cross-sectional study Mod Rheumatol. 2021 Sep;31(5):992-996. doi: 10.1080/14397595.2020.1840047. Epub 2020 Nov 6.doi: 10.1080/14397595.2020.1840047 PMID33084458

6. Tobimatsu H, Ikari K, Yano K, Okazaki K. Radiographic Factors Associated with Painful Callosities After Forefoot Surgery in Patients with Rheumatoid Arthritis Mod Rheumatol. 2021 Dec 23:roab131. doi: 10.1093/mr/roab131. Online ahead of print.doi: 10.1093/mr/roab131 PMID34939107

7. Tobimatsu H, Ikari K, Yano K, Okazaki K. Triple osteotomy for erosive first metatarsal in a patient with rheumatoid arthritis: a case report Mod Rheumatol Case Rep. 2021 Jan;5(1):6-10. doi: 10.1080/24725625.2020.1789303. Epub 2020 Jul 9.doi: 10.1080/24725625.2020.1789303 PMID33269650

8. Yano K, Tobimatsu H, Ikari K, Okazaki K. How reliable is assessment of joint swelling and tenderness over socks or stockings in patients with established rheumatoid arthritis? Mod Rheumatol. 2021 Nov 19:roab101. doi: 10.1093/mr/roab101. Online ahead of print.doi: 10.1093/mr/roab101 PMID34891174

9. Mochizuki T, Yano K, Ikari K, Okazaki K. Effects of romosozumab or denosumab treatment on the bone mineral density and disease activity for 6 months in patients with rheumatoid arthritis with severe osteoporosis: An open-label, randomized, pilot study Osteoporos Sarcopenia. 2021 Sep;7(3):110-114. doi: 10.1016/j.afos.2021.08.001. Epub 2021 Aug 27.doi: 10.1016/j.afos.2021.08.001 PMID34632114

10. Mochizuki T, Nasu Y, Yano K, Ikari K, Hiroshima R, Okazaki K. Foot and ankle functions and deformities focus on posterior tibial tendon dysfunction using magnetic resonance imaging in patients with rheumatoid arthritis Mod Rheumatol. 2021 Oct 6:roab084. doi: 10.1093/mr/roab084. Online ahead of print.doi: 10.1093/mr/roab084 PMID34918140

11. Mochizuki T, Yano K, Ikari K, Okazaki K. Efficacy of Intra-Articular Injection of 10 mg and 20 mg Triamcinolone for Rheumatoid Arthritis of the Wrist: A Prospective, Randomized, Pilot Study J Hand Surg Asian Pac Vol. 2021 Sep;26(3):490-493. doi: 10.1142/S2424835521200046.doi: 10.1142/S2424835521200046 PMID34380392

12. Yano K, Ikari K, Tobimatsu H, Tominaga A, Okazaki K. Joint-Preserving Surgery for Forefoot Deformities in Patients with Rheumatoid Arthritis: A Literature Review Int J Environ Res Public Health. 2021 Apr 13;18(8):4093. doi: 10.3390/ijerph18084093.doi: 10.3390/ijerph18084093 PMID33924481

13. Mochizuki T, Yano K, Ikari K, Okazaki K. Safety and Efficacy of Zoledronic Acid Treatment with and without Acetaminophen and Eldecalcitol for Osteoporosis Intern Med. 2021;60(16):2585-2591. doi: 10.2169/internalmedicine.6607-20. Epub 2021 Aug 15.doi: 10.2169/internalmedicine.6607-20 PMID34393156

14. Mochizuki T, Yano K, Ikari K, Okazaki K. Difference in patient-reported outcomes of various patellar component designs in total knee arthroplasty: A randomized clinical study J Orthop Surg (Hong Kong). 2021 Jan-Apr;29(1):2309499021996068. doi: 10.1177/2309499021996068.doi: 10.1177/2309499021996068 PMID33629887

 

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SLE

1. Kandane-Rathnayake R, Louthrenoo W, Luo SF, Wu YJ, Chen YH, Golder V, Lateef A, Cho J, Navarra SV, Zamora L, Hamijoyo L, Sockalingam S, An Y, Li Z, Montes R, Oon S, Katsumata Y, Harigai M, Hao Y, Zhang Z, Chan M, Kikuchi J, Takeuchi T, Goldblatt F, O'Neill S, Bae SC, Lau CS, Hoi A, Karyekar CS, Nikpour M, Morand EF; Asia-Pacific Lupus Collaboration. Patterns of Medication Use in Systemic Lupus Erythematosus - A Multi-Centre Cohort Study Arthritis Care Res (Hoboken). 2021 Jul 1. doi: 10.1002/acr.24740. Online ahead of print.doi: 10.1002/acr.24740 PMID34197023

2. Suetsugu H, Kim K, Yamamoto T, Bang SY, Sakamoto Y, Shin JM, Sugano N, Kim JS, Mukai M, Lee YK, Ohmura K, Park DJ, Takahashi D, Ahn GY, Karino K, Kwon YC, Miyamura T, Kim J, Nakamura J, Motomura G, Kuroda T, Niiro H, Miyamoto T, Takeuchi T, Ikari K, Amano K, Tada Y, Yamaji K, Shimizu M, Atsumi T, Seki T, Tanaka Y, Kubo T, Hisada R, Yoshioka T, Yamazaki M, Kabata T, Kajino T, Ohta Y, Okawa T, Naito Y, Kaneuji A, Yasunaga Y, Ohzono K, Tomizuka K, Koido M, Matsuda K, Okada Y, Suzuki A, Kim BJ, Kochi Y, Lee HS, Ikegawa S, Bae SC, Terao C. Novel susceptibility loci for steroid-associated osteonecrosis of the femoral head in systemic lupus erythematosus Hum Mol Genet. 2021 Dec 1:ddab306. doi: 10.1093/hmg/ddab306. Online ahead of print.doi: 10.1093/hmg/ddab306 PMID34850884

3. Tsuchiya K, Endo C, Kondo A, Fukuya Y, Honda S, Hirahara S, Majima M, Hanaoka M, Harigai M, Ishiguro N. A case of non-uremic calciphylaxis associated with systemic lupus erythematosus and antiphospholipid syndrome J Dermatol. 2021 Apr;48(4):e157-e158. doi: 10.1111/1346-8138.15765. Epub 2021 Feb 2.doi: 10.1111/1346-8138.15765 PMID33529397

4. Yin X, Kim K, Suetsugu H, Bang SY, Wen L, Koido M, Ha E, Liu L, Sakamoto Y, Jo S, Leng RX, Otomo N, Laurynenka V, Kwon YC, Sheng Y, Sugano N, Hwang MY, Li W, Mukai M, Yoon K, Cai M, Ishigaki K, Chung WT, Huang H, Takahashi D, Lee SS, Wang M, Karino K, Shim SC, Zheng X, Miyamura T, Kang YM, Ye D, Nakamura J, Suh CH, Tang Y, Motomura G, Park YB, Ding H, Kuroda T, Choe JY, Li C, Niiro H, Park Y, Shen C, Miyamoto T, Ahn GY, Fei W, Takeuchi T, Shin JM, Li K, Kawaguchi Y, Lee YK, Wang Y, Amano K, Park DJ, Yang W, Tada Y, Yamaji K, Shimizu M, Atsumi T, Suzuki A, Sumida T, Okada Y, Matsuda K, Matsuo K, Kochi Y; Japanese Research Committee on Idiopathic Osteonecrosis of the Femoral Head, Kottyan LC, Weirauch MT, Parameswaran S, Eswar S, Salim H, Chen X, Yamamoto K, Harley JB, Ohmura K, Kim TH, Yang S, Yamamoto T, Kim BJ, Shen N, Ikegawa S, Lee HS, Zhang X, Terao C, Cui Y, Bae SC. Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus Ann Rheum Dis. 2021 May;80(5):632-640. doi: 10.1136/annrheumdis-2020-219209. Epub 2020 Dec 3.doi: 10.1136/annrheumdis-2020-219209 PMID33272962

5. Okamoto Y, Katsumata Y, Baba S, Kawaguchi Y, Harigai M. Validation of the Japanese version of the Lupus Damage Index Questionnaire in a large observational cohort: A two-year prospective study Mod Rheumatol. 2021 Jul;31(4):834-842. doi: 10.1080/14397595.2020.1829341. Epub 2020 Oct 13.doi: 10.1080/14397595.2020.1829341PMID32990111

6. Kandane-Rathnayake R, Louthrenoo W, Golder V, Luo SF, Wu YJ, Lateef A, Cho J, Li Z, An Y, Hamijoyo L, Navarra S, Zamora L, Katsumata Y, Harigai M, Sockalingam S, Chan M, Chen YH, O'Neill S, Goldblatt F, Hao Y, Zhang Z, Kikuchi J, Takeuchi T, Lau CS, Nikpour M, Morand E, Hoi A; Asia Pacific Lupus Collaboration. Independent associations of lymphopenia and neutropenia in patients with systemic lupus erythematosus: a longitudinal, multinational study Rheumatology (Oxford). 2021 Nov 3;60(11):5185-5193. doi: 10.1093/rheumatology/keab217.doi: 10.1093/rheumatology/keab217 PMID33693676

 

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全身性強皮症

1. Takagi K, Kawamoto M, Higuchi T, Tochimoto A, Hirose H, Harigai M, Kawaguchi Y. Characteristics of Japanese patients with systemic sclerosis complicated with calcinosis Int J Rheum Dis. 2021 Jun;24(6):803-808. doi: 10.1111/1756-185X.14121. Epub 2021 Apr 28.doi: 10.1111/1756-185X.14121 PMID33909342
強皮症の皮下や筋膜組織内の石灰化は、晩期のCREST症候群で認められる。しかし、びまん皮膚硬化型の強皮症では早期の段階で石灰化が出現することをしばしば経験する。本研究で、当院に通院中の416名の強皮症患者においての石灰化の頻度は24%であった。石灰化と関連する強皮症の臨床症状は、びまん皮膚硬化型、抗Scl70抗体、爪郭部の出血であった。

2. Kuwana M, Hasegawa M, Fukue R, Shirai Y, Ishikawa O, Endo H, Ogawa F, Goto D, Kawaguchi Y, Sato S, Ihn H, Takehara K. Initial predictors of skin thickness progression in patients with diffuse cutaneous systemic sclerosis: Results from a multicentre prospective cohort in Japan Mod Rheumatol. 2021 Mar;31(2):386-393. doi: 10.1080/14397595.2020.1784548. Epub 2020 Jul 20.doi: 10.1080/14397595.2020.1784548 PMID32552202

3. Utsunomiya A, Hasegawa M, Oyama N, Asano Y, Endo H, Fujimoto M, Goto D, Ishikawa O, Kawaguchi Y, Kuwana M, Ogawa F, Takahashi H, Tanaka S, Sato S, Takehara K, Ihn H. Clinical course of Japanese patients with early systemic sclerosis: A multicenter, prospective, observational study Mod Rheumatol. 2021 Jan;31(1):162-170. doi: 10.1080/14397595.2020.1751408. Epub 2020 Apr 21.doi: 10.1080/14397595.2020.1751408 PMID32243215

 

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皮膚筋炎/多発筋炎

1. Ichimura Y, Konishi R, Shobo M, Inoue S, Okune M, Maeda A, Tanaka R, Kubota N, Matsumoto I, Ishii A, Tamaoka A, Shimbo A, Mori M, Morio T, Kishi T, Miyamae T, Tanboon J, Inoue M, Nishino I, Fujimoto M, Nomura T, Okiyama N. Anti-nuclear matrix protein 2 antibody-positive inflammatory myopathies represent extensive myositis without dermatomyositis-specific rash Rheumatology (Oxford). 2021 Jun 21:keab518. doi: 10.1093/rheumatology/keab518. Online ahead of print.doi: 10.1093/rheumatology/keab518 PMID34152410

2. Gono T, Masui K, Nishina N, Kawaguchi Y, Kawakami A, Ikeda K, Kirino Y, Sugiyama Y, Tanino Y, Nunokawa T, Kaneko Y, Sato S, Asakawa K, Ukichi T, Kaieda S, Naniwa T, Okano Y, Kuwana M; the Multicenter Retrospective Cohort of Japanese Patients with Myositis-Associated ILD (JAMI) Investigators. Risk Prediction Modeling Based on a Combination of Initial Serum Biomarker Levels in Polymyositis/Dermatomyositis-Associated Interstitial Lung Disease Arthritis Rheumatol. 2021 Apr;73(4):677-686. doi: 10.1002/art.41566. Epub 2021 Feb 22.doi: 10.1002/art.41566 PMID33118321

3. Yoshida A, Katsumata Y, Hirahara S, Hanaoka M, Ochiai M, Kobayashi M, Harigai M. Tumour necrosis factor inhibitor-induced myositis in a patient with ulcerative colitis Mod Rheumatol Case Rep. 2021 Jan;5(1):156-161. doi: 10.1080/24725625.2020.1800958. Epub 2020 Aug 6.doi: 10.1080/24725625.2020.1800958 PMID32757711

 

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血管炎

1. Yokoe Y, Tsuboi N, Imaizumi T, Kitagawa A, Karasawa M, Ozeki T, Endo N, Sawa Y, Kato S, Katsuno T, Maruyama S, Yamagata K, Usui J, Nagata M, Sada KE, Sugiyama H, Amano K, Arimura Y, Atsumi T, Yuzawa Y, Dobashi H, Takasaki Y, Harigai M, Hasegawa H, Makino H, Matsuo S; Japan Research Committee of the Ministry of Health, Labour, and Welfare for Intractable Vasculitis and for Intractable Renal Disease. Clinical impact of urinary CD11b and CD163 on the renal outcomes of anti-neutrophil cytoplasmic antibody-associated glomerulonephritis Nephrol Dial Transplant. 2021 Jul 23;36(8):1452-1463. doi: 10.1093/ndt/gfaa097.doi: 10.1093/ndt/gfaa097 PMID32639002

2. Ishizaki J, Takemori A, Horie K, Hiraoka D, Suemori K, Matsumoto T, Sada KE, Amano K, Harigai M, Arimura Y, Makino H, Takenaka K, Takemori N, Hasegawa H; Research Committee of Intractable Vasculitis Syndrome and the Research Committee of Intractable Renal Disease of the Ministry of Health, Labour and Welfare of Japan. Usefulness of tissue inhibitor of metalloproteinase 1 as a predictor of sustained remission in patients with antineutrophil cytoplasmic antibody-associated vasculitis Arthritis Res Ther. 2021 Mar 20;23(1):91. doi: 10.1186/s13075-021-02471-5.doi: 10.1186/s13075-021-02471-5 PMID33743769

3. Kawazoe M, Nanki T, Hagino N, Ikegaya N, Ito S, Kodera M, Nakano N, Suzuki M, Kaname S, Harigai M. Clinical characteristics of patients with polyarteritis nodosa based on a nationwide database in Japan Mod Rheumatol. 2021 Aug 12:roab019. doi: 10.1093/mr/roab019. Online ahead of print.doi: 10.1093/mr/roab019 PMID34894268

4. Watanabe H, Sada KE, Harigai M, Amano K, Dobashi H, Takasaki Y, Fujimoto S, Atsumi T, Yamagata K, Homma S, Arimura Y, Makino H; Research Committee of Intractable Vasculitis Syndrome (JPVAS); Research Committee of Intractable Renal Disease of the Ministry of Health, Labour, and Welfare of Japan. Exploratory classification of clinical phenotypes in Japanese patients with antineutrophil cytoplasmic antibody-associated vasculitis using cluster analysis Sci Rep. 2021 Mar 4;11(1):5223. doi: 10.1038/s41598-021-84627-6.doi: 10.1038/s41598-021-84627-6 PMID33664381

5. Sugihara T, Nakaoka Y, Uchida HA, Yoshifuji H, Maejima Y, Watanabe Y, Amiya E, Tanemoto K, Miyata T, Umezawa N, Manabe Y, Ishizaki J, Shirai T, Nagafuchi H, Hasegawa H, Miyamae T, Niiro H, Ito S, Ishii T, Isobe M, Harigai M. Establishing Clinical Remission Criteria and the Framework of a Treat-To-Target Algorithm for Takayasu arteritis: Results of a Delphi Exercise Carried out by an Expert Panel of the Japan Research Committee of the Ministry of Health, Labour, and Welfare for intractable vasculitis Mod Rheumatol. 2021 Nov 27:roab081. doi: 10.1093/mr/roab081. Online ahead of print.doi: 10.1093/mr/roab081 PMID34850081

6. Nagasaka K, Kaname S, Amano K, Kato M, Katsumata Y, Komagata Y, Sada KE, Tanaka E, Tamura N, Dobashi H, Nanki T, Harabuchi Y, Bando M, Homma S, Wada T, Harigai M. Nation-wide survey of the treatment trend of microscopic polyangiitis and granulomatosis with polyangiitis in Japan using the Japanese Ministry of Health, Labour and Welfare Database Mod Rheumatol. 2021 Oct 7:roab088. doi: 10.1093/mr/roab088. Online ahead of print.doi: 10.1093/mr/roab088 PMID34918136

7. Watanabe H, Sada KE, Matsumoto Y, Harigai M, Amano K, Fujimoto S, Dobashi H, Yuzawa Y, Yamagata K, Muso E, Arimura Y, Makino H. Rationale of concomitant cyclophosphamide for remission-induction in patients with antineutrophil cytoplasmic antibody-associated vasculitis: A propensity score-matched analysis of two nationwide prospective cohort studies Mod Rheumatol. 2021 Jan;31(1):205-213. doi: 10.1080/14397595.2019.1707997. Epub 2020 Jan 6.doi: 10.1080/14397595.2019.1707997 PMID31859544

 

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小児リウマチ科


1. Kishi T, Sakai R, Tani Y, Nagata S, Katsumata Y, Miyamae T, Harigai M. Trends in actual medication use for child-onset systemic lupus erythematosus using the Japanese health insurance database 2009-18 Mod Rheumatol. 2021 Aug 11:roab038. doi: 10.1093/mr/roab038. Online ahead of print.doi: 10.1093/mr/roab038 PMID34908147
国内多施設の医事会計データを使用し、182例の小児SLE患者の2009年から10年間の薬剤処方状況を解析した。10年間で、グルココルチコイドの投与量は減少傾向にあり、使用する主な免疫抑制剤がミコフェノール酸モフェチルへが主流と変化してきたことを報告した。

2. Kishi T, Tani Y, Okiyama N, Mizuochi K, Ichimura Y, Harigai M, Nagata S, Miyamae T. Anti-SAE autoantibody-positive Japanese patient with juvenile dermatomyositis complicated with interstitial lung disease - a case report Pediatr Rheumatol Online J. 2021 Mar 19;19(1):34. doi: 10.1186/s12969-021-00532-2.doi: 10.1186/s12969-021-00532-2 PMID33740993

3. Tanaka R, Tani Y, Kaburaki Y, Kinoshita M, Kawaguchi Y, Okazaki Y, Kuwana M, Harigai M, Nagata S, Miyamae T. Joint contractures responsive to immunosuppressive therapy in a girl with childhood-onset systemic sclerosis double-seropositive for rare anti-nucleolar autoantibodies: a case report Pediatr Rheumatol Online J. 2021 Mar 20;19(1):37. doi: 10.1186/s12969-021-00525-1.doi: 10.1186/s12969-021-00525-1 PMID33743728

4. Mori M, Akioka S, Igarashi T, Inoue Y, Umebayashi H, Ohshima S, Nishiyama S, Hashimoto M, Matsui T, Miyamae T, Yasumi T. Transitioning from paediatric to adult rheumatological healthcare: English summary of the Japanese Transition Support Guide Mod Rheumatol. 2021 Sep 24:roab071. doi: 10.1093/mr/roab071. Online ahead of print.doi: 10.1093/mr/roab071 PMID34918115

5. Igarashi K, Hori T, Yamamoto M, Hatakeyama N, Iesato K, Takebayashi A, Kizawa T, Miyamae T, Kawamoto M, Kawasaki Y. Familial Mediterranean Fever After Cord Blood Transplantation for Familial Hemophagocytic Lymphohistiocytosis J Pediatr Hematol Oncol. 2021 Nov 1;43(8):e1136-e1139. doi: 10.1097/MPH.0000000000002081.doi: 10.1097/MPH.0000000000002081 PMID33560083

6. Mamyrova G, Kishi T, Shi M, Targoff IN, Huber AM, Curiel RV, Miller FW, Rider LG; Childhood Myositis Heterogeneity Collaborative Study Group. Anti-MDA5 autoantibodies associated with juvenile dermatomyositis constitute a distinct phenotype in North America Rheumatology (Oxford). 2021 Apr 6;60(4):1839-1849. doi: 10.1093/rheumatology/keaa429.doi: 10.1093/rheumatology/keaa429 PMID33140079

7. Miyamae T, Kawabe T. Non-Criteria Manifestations of Juvenile Antiphospholipid Syndrome J Clin Med. 2021 Mar 17;10(6):1240. doi: 10.3390/jcm10061240.doi: 10.3390/jcm10061240 PMID33802787

8. Kishi T, Warren-Hicks W, Bayat N, Targoff IN, Huber AM, Ward MM, Rider LG; with the Childhood Myositis Heterogeneity Study Group. Corticosteroid discontinuation, complete clinical response and remission in juvenile dermatomyositis Rheumatology (Oxford). 2021 May 14;60(5):2134-2145. doi: 10.1093/rheumatology/keaa371.doi: 10.1093/rheumatology/keaa371 PMID33067611

9. Yamazaki K, Ohta A, Akioka S, Yamasaki Y, Ohara A, Nakaseko H, Nishimura K, Kobayashi N, Nishida Y, Sato S, Takezaki S, Kishi T, Hashimoto M, Kobayashi I, Mori M; group of Juvenile Idiopathic Inflammatory Myopathies in the Research Team for Pediatric Rheumatic Disease, The Research Program for Intractable Disease of the Ministry of Health, Labor and Welfare. External validation of the EULAR/ACR idiopathic inflammatory myopathies classification criteria with a Japanese paediatric cohort Rheumatology (Oxford). 2021 Feb 1;60(2):802-808. doi: 10.1093/rheumatology/keaa274.doi: 10.1093/rheumatology/keaa274 PMID32810274

10. Yamasaki Y, Kobayashi N, Akioka S, Yamazaki K, Takezaki S, Nakaseko H, Ohara A, Nishimura K, Nishida Y, Sato S, Kishi T, Hashimoto M, Mori M, Okazaki Y, Kuwana M, Ohta A. Clinical impact of myositis-specific autoantibodies on long-term prognosis of juvenile idiopathic inflammatory myopathies: multicentre study Rheumatology (Oxford). 2021 Oct 2;60(10):4821-4831. doi: 10.1093/rheumatology/keab108.doi: 10.1093/rheumatology/keab108 PMID33576399

11. Miyamae T, Inoue Y, Yamaguchi K. Checklist for rapid assessment of independence in children with pediatric rheumatic diseases in transition to adult medical care Mod Rheumatol. 2021 Aug 31:1918858. doi: 10.1080/14397595.2021.1918858. Online ahead of print.doi: 10.1080/14397595.2021.1918858 PMID34931248

12. Ichimura Y, Konishi R, Shobo M, Inoue S, Okune M, Maeda A, Tanaka R, Kubota N, Matsumoto I, Ishii A, Tamaoka A, Shimbo A, Mori M, Morio T, Kishi T, Miyamae T, Tanboon J, Inoue M, Nishino I, Fujimoto M, Nomura T, Okiyama N. Reliability of antinuclear matrix protein 2 antibody assays in idiopathic inflammatory myopathies is dependent on target protein properties J Dermatol. 2021 Dec 29. doi: 10.1111/1346-8138.16295. Online ahead of print.doi: 10.1111/1346-8138.16295 PMID34967032

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その他

1. Yokota S, Miyamae T, Kuroiwa Y, Nishioka K. Novel Coronavirus Disease 2019 (COVID-19) and Cytokine Storms for More Effective Treatments from an Inflammatory Pathophysiology J Clin Med. 2021 Feb 17;10(4):801. doi: 10.3390/jcm10040801.doi: 10.3390/jcm10040801 PMID33671159

2. Ogasawara Y, Kogiso T, Kotera Y, Omori A, Konda N, Sugano E, Sagawa T, Taniai M, Harigai M, Egawa H, Yamamoto M, Tokushige K. The utility of liver transplantation to treat acute liver failure caused by adult-onset Still's disease: case reports Clin J Gastroenterol. 2021 Jun;14(3):866-875. doi: 10.1007/s12328-021-01398-3. Epub 2021 Apr 1.doi: 10.1007/s12328-021-01398-3 PMID33797038

3. Kondoh Y, Makino S, Ogura T, Suda T, Tomioka H, Amano H, Anraku M, Enomoto N, Fujii T, Fujisawa T, Gono T, Harigai M, Ichiyasu H, Inoue Y, Johkoh T, Kameda H, Kataoka K, Katsumata Y, Kawaguchi Y, Kawakami A, Kitamura H, Kitamura N, Koga T, Kurasawa K, Nakamura Y, Nakashima R, Nishioka Y, Nishiyama O, Okamoto M, Sakai F, Sakamoto S, Sato S, Shimizu T, Takayanagi N, Takei R, Takemura T, Takeuchi T, Toyoda Y, Yamada H, Yamakawa H, Yamano Y, Yamasaki Y, Kuwana M; joint committee of Japanese Respiratory Society and Japan College of Rheumatology. 2020 guide for the diagnosis and treatment of interstitial lung disease associated with connective tissue disease Respir Investig. 2021 Nov;59(6):709-740. doi: 10.1016/j.resinv.2021.04.011. Epub 2021 Oct 1.doi: 10.1016/j.resinv.2021.04.011 PMID34602377

 

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