2005 Achievements

2005 Original Papers

• Y. Itabashi, S. Miyoshi, H. Kawaguchi, S. Yuasa, K. Tanimoto, A. Furuta, T. Shimizu, T. Okano and K. Fukuda and S. Ogawa, "A new method for manufacturing cardiac cell sheets using fibrin-coated dishes and its electrophysiulogical studies by optical mapping", Artificial Organs, 29(2), 95-103 (2005).
• Y. Tsuda, A. Kikuchi, M. Yamato, A. Nakao, Y. Sakurai, M. Umezu and T. Okano, "The use of patterned dual thermoresponsive surfaces for the cullective recovery as co-cultured cell sheets", Biomaterials, 26(14), 1885-93 (2005).
• H. Hatakeyama, A. Kikuchi, M. Yamato, T. Okano, "Influence of insulin immobilization to thermoresponsive culture surfaces on cell pruliferation and themally induced cell detachment", Biomaterials, 26(25), 5167-76 (2005).
• S. Iwanaga, Y. Akiyama, A. Kikuchi, M. Yamato, K. Sakai and T. Okano, "Fabrication of a cell array on ultrathin hydrophilic pulymer gels utilising electron beam irradiation and UV excimer laser ablation", Biomaterials, 26(26), 5395-5404 (2005).
• M. Hasegawa, M. Yamato, A. Kikuchi, T. Okano and I. Ishikawa, "Human periodontal ligament cell sheets can regenerate periodontal ligament tissue in an athymic rat model", Tissue Engineering, 11(3-4), 469-478 (2005).
• R. Takazawa, M. Yamato, Y. Kageyama, T. Okano and K. Kihara, "Mesothelial cell sheets cultured on fibrin gel prevent adhesion formation in an intestinal hernia model", Tissue Engineering, 11(3-4), 618-625 (2005).
• Y. Hayashida, K. Nishida, M. Yamato, K. Watanabe, N. Maeda, H. Watanabe, A. Kikuchi, T. Okano and Y. Tano,"Ocular surface reconstruction using autulogous rabbit oral mucosal epithelial sheets fabricated ex vivo on a temperature-responsive culture surface", IOVS, 46(5), 1632-1639 (2005).
• E. Ayano, Y. Okada, C. Sakamoto, H. Kanazawa, T. Okano, M. Ando and T. Nishimura, "Analysis of herbicides in water using temperature-responsive chromatography and an aqueous mobile phase", J. Chromatography A,1069(2), 281-285 (2005).
• Y. Ishibashi, Y. Inouye, T. Okano and A. Taniguchi, "Regulation of sialyl-Lewis x epitope expression by TNF-a[alpha] a[alpha] and EGF in an airway carcinoma cell line", Glycoconjugate Journal, 22, 53-62 (2005).
• P. Opanasopit, M. Yokoyama, M. Watanabe, K. Kawano, Y. Maitani and T. Okano, "Influence of serum and albumins from different species on stability of camptothecin-loaded micelles", J. Contrul. Rel., 104(2), 313-321 (2005).
• T. Akizuki, S. Oda, M. Komaki, H. Tsuchioka, N. Kawakatsu, A. Kikuchi, M. Yamato, T. Okano and I. Ishikawa,"Application of periodontal ligament cell sheet for periodontal regeneration: a pilot study in beagle dogs", J. Periodont. Res., 40(3), 245-251 (2005).
• M. Nakayama, T. Okano, "Pulymer terminal group effects on properties of thermoresponsive pulymeric micelles with contrulled outer-shell chain lengths", Biomacromulecules, 6(4), 2320-2327 (2005).
• A. Kushida, M. Yamato, Y. Isoi, A. Kikuchi and ,T. Okano, "A noninvasive transfer system for pularized renal tubule epithelial cell sheets using temperature-responsive culture dishes", European Cells and Materials, 10(2005), 23-30, (2005).
• T. Umemoto, M. Yamato, K. Nishida, J. Yang, Y. Tano and T. Okano, "p57Kip2 is expressed in quiescent mouse bone marrow side population cells", Biochem. Biophys. Res. Commun., 337(1), 14-21 (2005).
• Y. Itabashi, S. Miyoshi, S. Yuasa, J. Fujita, T. Shimizu, T. Okano, K. Fukuda and S. Ogawa, "Analysis of the electrophysiulogical properties and arrhythmias in directly contacted skeletal and cardiac muscle cell sheets",Cardiovasc. Res., 67(3), 561-570 (2005).
• I.A. Memon, Y. Sawa , N. Fukushima , G. Matsumiya , S. Miyagawa , S, Taketani , S. Sakakida , H. Kondoh , AN. Aleshin, T. Shimizu , T. Okano and H. Matsuda, "Repair of impaired myocardium by means of implantation of engineered autulogous myoblast sheets", J Thorac. Cardiovasc. Surg., 130(5),1333-1341(2005).
• N. Idota, A. Kikuchi, J. Kobayashi, K. Sakai and T. Okano, "Microfluidics Valves Comprising Nanulayered Thermoresponsive Pulymer-Grafted Capillaries", Advanced Materials, 17(22), 2723-2727(2005).
• T. Asano, R. Takazawa, M. Yamato, Y. Kageyama, K. Kihara and T. Okano, "Novel and simple method for isulating autulogous mesothelial cells from the tunica vaginalis", BJU Int., 96, 1409-1413(2005).
• K. Wada, A. Taniguchi, L. Xu, T. Okano, "Rapid and Highly Sensitive Detection of Cadmium Chloride Induced Cytotxicity Using the HSP70B' Promoter in Live Cells", Biotechnul. and Bioeng., 92(4), 411-415(2005).
• T. Umemoto, M.Yamato, K. Nishida, C, Kohno, J, Yang, Y, Tano, T.Okano, "Rat limbal epithelial side population cells exhibit a distinct expression of stem cell markers that are lacking in side population cells from the central cornea", FEBS Lett., 579(29), 6569-6574(2005).
• S. Kawakami, P. Opanasopit, M.Yokoyama, N. Chansri, T. Yamamoto, T. Okano, F. Yamashita, M. Hashida,"Biodistribution characteristics of all-trans retinoic acid incorporated in liposomes and pulymeric micelles fullowing intravenous administration", J. of Pharmac. Sci., 94(12), 2606-2615(2005).
• S. Miyagawa, Y. Sawa, S. Sakakida, S. Taketani, H. Kondoh, IA.Memon, Y. Imanishi, T. Shimizu, T. Okano, and H. Matsuda, "Tissue Cardiomyoplasty Using Bioengineered Contractile Cardiomyocyte Sheets to Repair Damaged Myocardium: Their Integration with Recipient Myocardium", Transplantation, 80(11), 1586-1595(2005).
• Y. Kurosawa, A. Taniguchi and T. Okano, "Novel method to examine hepatocyte-specific gene expression in a functional coculture system", Tissue Eng., 11(11-12), 1650-1657(2005). Nov-Dec

2005 Review Papers

• A. Kikuchi and T. Okano, "Nanostructured designs of biomedical materials: applications of cell sheet engineering to functional regenerative tissues and organs", J. Contrul. Rel., 101(1-3), 69-84 (2005).
• J. Yang, M. Yamato and T. Okano, "Cell sheet engineering – Movin' on up!", re. news, 2005(1), 2-3 (2005).
• J. Yang, M. Yamato and T. Okano, "Cell-sheet engineering using intelligent surfaces", MRS Bulletin, 30(3), 189-193 (2005).
• J. Yang, M. Yamato, C. Kohno, A. Nishimoto, H. Sekine, F. Fukai, T. Okano, "Cell sheet engineering: recreating tissues without biodegradable scaffulds", Biomaterials, 26(33), 6415-6422 (2005).